Overview

This knowledge graph maps 25 years of NASA research on how the model plant Arabidopsis thaliana responds to spaceflight. As humanity plans long-duration missions to Mars and beyond, understanding plant biology in space is critical for developing sustainable life support systems.

The graph synthesizes findings from over 120 publications, connecting molecular mechanisms (gene expression, epigenetics, hormone signaling) to observable phenotypes (root growth, cell wall structure, stress responses). It reveals how plants have evolved to use gravity as a developmental cue—and what happens when that cue is removed.

This resource serves space biologists planning ISS experiments, plant scientists studying gravitropism, and engineers designing controlled environment agriculture for future space habitats.

What's in This Graph

• **3,475 knowledge nodes** covering molecular, cellular, and organism-level responses to spaceflight
• **120+ source publications** from NASA GeneLab, Plant Physiology, and Frontiers in Plant Science
• **7 node types** including Factors, Instruments (Veggie, KFT), Protocol Steps, and Evidence Lines
• **Transcriptomic data** showing which genes are up/down-regulated in microgravity
• **Epigenetic changes** including DNA methylation patterns and chromatin modifications
• **Hardware documentation** for ISS plant growth systems (Veggie, ABRS, KFT)

Questions You Can Explore

• How do plants sense and respond to microgravity?
• What genes are upregulated during spaceflight?
• How does the phytochrome light switch work?
• What happens to plant cell walls in space?
• How does auxin distribution change without gravity?
• What epigenetic changes occur in space-grown plants?

Data Access

Download: JSON Data

Citation: Fylo. (2025). NASA Arabidopsis Space Biology Knowledge Graph. https://fylo.io/nasa

License: CC BY 4.0 - Free to use with attribution